Do not use products containing ibuprofen in children under 6 months of age without first talking to your health care provider. Always use the dosage indicated in the product instructions or as recommended by your health care provider. Reye Syndrome occurs 3 to 7 days after the beginning of an infection or illness caused by a virus, or during recovery from the infection or illness.
Reye Syndrome can be misdiagnosed as swelling of the brain, also known as encephalitis or swelling of the lining of the brain meningitis , diabetes, drug overdose, poisoning, sudden infant death syndrome SIDS or a psychiatric illness.
Treatment includes reducing brain swelling, preventing damage to the liver and other organs and monitoring the heart. Skip to main content. Last Updated:. January These conditions include metabolic disorders such as defects in fatty acid oxidation including acyl-CoA dehydrogenase deficiencies , disorders of oxidative phosphorylation, urea-cycle defects, disorders of carbohydrate metabolism, other metabolic disorders and errors of inborn metabolism, CNS infection or meningitis, and drug or toxic ingestion.
Disorders causing presentation with acute liver failure should also be ruled out. It begins as a prodromal febrile illness that is likely viral in nature, such as an upper respiratory infection or varicella, or possibly rotavirus.
Patients will often present with some degree of hepatomegaly and hepatic dysfunction due to fatty degeneration of the liver, but they will not be icteric. There also may be an elevation of intracranial pressure. Early diagnosis is important, and other diseases causing similar symptoms must be ruled out. Coagulopathies may be managed with blood transfusions, and intubation may be necessary to provide adequate oxygenation.
Intracranial pressure must be monitored and controlled in patients with cerebral edema. Management of cerebral edema may involve fluid restriction, diuresis, and corticosteroids.
Pentobarbital has been given to patients to decrease cerebral metabolic demands. In patients who develop seizures, antiepileptic medications may be necessary. Aspirin is considered to be the most significant causative agent, although this association is often challenged. Pharmacists can play a role in ensuring the appropriate use of aspirin in the pediatric population. A risk-benefit assessment must be done on a patient-by-patient basis.
While the benefit likely outweighs the risk in patients with disorders such as Kawasaki disease, the pharmacist can play a role in ensuring that these patients receive their influenza vaccination to decrease their chance of viral illness during their aspirin therapy. In otherwise healthy children, the use of aspirin as an antipyretic or anti-inflammatory agent is not recommended because the benefit likely does not outweigh the risk. In this circumstance, the pharmacist can play an important role in recommending an alternative agent, such as ibuprofen or acetaminophen.
Encephalopathy and fatty degeneration of the viscera: a disease entity in childhood. Aspirin and Reye syndrome: a review of the evidence.
Paediatr Drugs. Fitzgerald DA. Aspirin and Reye syndrome. Giles HM. Encephalopathy and fatty degeneration of the liver. Reassessing Reye syndrome. Arch Pediatr Adolesc Med. N Engl J Med. J Infect Dis. Gosalakkal JA, Kamoji V. Reye syndrome and Reye-like syndrome. Here's one dad's take on how to raise boys to be emotionally healthy.
Parenting isn't easy, and parental burnout can make it even harder to take care of yourself and your kids. Here are some tips. Experts encourage parents to avoid strict limits on Halloween candy as they can make the treats more enticing.
Atopic dermatitis in children can be a difficult diagnosis to hear — but as a parent, you can definitely make your little one a lot more comfortable…. A medical expert answers common questions about having children younger than 12 years old vaccinated against COVID Health Conditions Discover Plan Connect. Medically reviewed by Karen Gill, M. Prevalence and risk factors.
Read this next. Medically reviewed by Susan J. Bliss, R. Can Aspirin Treat Acne? Hyperviscosity Syndrome. Medically reviewed by Judith Marcin, M. What to Know About Holiday Gatherings with Unvaccinated Kids Though vaccines for younger children are now available, they may not be fully protected in time for holiday celebrations this year. Medically reviewed by Carissa Stephens, R. Medically reviewed by Debra Sullivan, Ph.
0コメント